TABLE A1.

Example of data used to determine response rates

MIC (mg/liter)	Fraction of distribution at the indicated MIC	Fractional target attainment (90% Emax) at the MIC	Product of fractions
0.016	0.001	1.0	0.001
0.023	0.001	1.0	0.001
0.032	0.003	1.0	0.003
0.047	0.002	1.0	0.002
0.064	0.015	1.0	0.015
0.094	0.048	1.0	0.048
0.125	0.124	0.996	0.124
0.19	0.099	0.736	0.073
0.25	0.145	0.38	0.055
0.38	0.159	0.083	0.013
0.5	0.162	0.034	0.0055
0.75	0.096	0.012	0.0012
1.0	0.077	0.004	0.0003
1.5	0.043	0.0	0
2.0	0.017	0.0	0
3.0	0.003	0.0	0
4.0	0.002	0.0	0
6.0	0.001	0.0	0