Table 3.
Effects of different pressure support levels on breathing pattern, inspiratory effort, and respiratory mechanics (fifteen patients).
| N = 15 | NIV PS5 | NIV PS10 | P value |
|---|---|---|---|
| RR, breaths per minute; mean ± SD (median; iqr25-iqr75) |
22,8±5 (22; 21- 23,75) |
21,4±7 (23,5; 18- 26) |
>0,05 |
| MeanVT, ml; mean ± SD (median; iqr25-iqr75) |
400,4±96,3 (391,6; 362,6-460,3) |
489,9±123,9 (458,2; 382,5-555,5) |
>0,05 |
| VT/PBW, ml/KGPBW; mean ± SD (median; iqr25-iqr75) |
5,8±1,4 (6,4; 4,8- 6,6) |
7±1,3 (7,1; 6 -7,8) |
>0,05 |
| Mean Ve, L/m; mean ± SD (median; iqr25-iqr75) |
9±2,1 (8,9; 8- 9,5) |
10,1±2,7 (9,4; 8,4-11,5) |
>0,05 |
| Mean ΔPes, cmH20; mean ± SD (median; iqr25-iqr75) |
-3,9±3,38 (-4,9; -2,1 - -5,9) |
-0,03±3,2 (1,4; -2,28 - +1,7) |
0,007 |
| Mean ΔPLDyn, cmH20; mean ± SD (median; iqr25-iqr75) |
8,8±3,6 (8,9; 7,3 – 11,1) |
10,6±2,2 (10,4; 8,6-12,1) |
>0,05 |
(NIV= non-invasive mechanical ventilation; RR =Respiratory Rate; Ve= minute ventilation, VT = tidal volume; PBW=Predicted body weight; ΔPes = tidal change in esophageal pressure, ΔPLDyn= Dynamic tidal change in transpulmonary pressure).
Patient consent: Obtained.
Ethics approval: Comitato Etico Indipendente dell'Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi.