. 2022 Apr 22;2:100025. doi: 10.1016/j.crchbi.2022.100025

Table 1.

Native mass spectrometry analysis of halicin-bound M^Pro.

	Unbound protein	Bound protein	Calculated Ligand Molecular Weight	Theoretical Ligand Molecular Weight
Monomer	33,796	33,923	127	128
Dimer	67,592	67,848	128 (Gates, 2020)	128

(Gates, 2020) A dimer can bind two inhibitors. The calculated ligand molecular weight. $= \frac{M W_{b o u n d} - M W_{u n b o u n d}}{2}$