Table 4.
Multivariate linear regression analyses of the factor score of “vegetables and fruits pattern” on QoL in Chinese women with early-stage breast cancer at 18-month follow-up
| EORTC QLQ-C30 | Univariate analysis | Model 1 | Model 2 | |||
|---|---|---|---|---|---|---|
| B (95%CI) | P | B (95%CI) | P | B (95%CI) | P | |
| Global health status/QoL | 1.693 (− 0.712 to 2.674) | 0.003 | 1.847 (0.739 to 2.956) | 0.004 | 2.195 (0.862 to 3.529) | 0.002 |
| Functioning | ||||||
| Physical functioning | 0.487 (− 0.144 to 1.118) | 0.132 | 0.367 (− 0.348 to 1.082) | 0.337 | 0.741 (− 0.120 to 1.601) | 0.121 |
| Role functioning | − 0.259 (− 1.082 to 0.564) | 0.790 | 0.346 (− 0.589 to 1.282) | 0.249 | 0.089 (− 1.037 to 1.215) | 0.465 |
| Emotional functioning | 0.411 (− 0.640 to 1.462) | 0.363 | 0.928 (− 0.261 to 2.116) | 0.305 | 1.391 (− 0.039 to 2.821) | 0.210 |
| Cognitive functioning | − 0.074 (− 1.142 to 0.993) | 0.865 | − 0.069 (− 1.291 to 1.154) | 0.983 | 0.613 (− 0.857 to 2.083) | 0.357 |
| Social functioning | − 0.457 (− 1.332 to 0.417) | 0.327 | − 0.079 (− 1.078 to 0.919) | 0.873 | 0.120 (− 1.082 to 1.322) | 0.754 |
| Symptoms | ||||||
| Fatigue | 0.453 (− 0.653 to 1.560) | 0.873 | 0.313 (− 0.944 to 1.569) | 0.815 | − 0.630 (− 2.139 to 0.879) | 0.102 |
| Nausea and vomiting | − 0.228 (− 0.592 to 0.137) | 0.517 | − 0.240 (− 0.654 to 0.174) | 0.449 | − 0.318 (− 0.816 to 0.180) | 0.542 |
| Pain | 0.321 (− 0.968 to 1.610) | 0.892 | 0.056 (− 1.395 to 1.508) | 0.763 | − 0.453 (− 2.200 to 1.293) | 0.381 |
| Dyspnea | 0.188 (− 0.761 to 1.138) | 0.683 | 0.090 (− 0.991 to 1.171) | 0.959 | − 0.747 (− 2.046 to 0.552) | 0.224 |
| Insomnia | 0.121 (− 1.486 to 1.728) | 0.699 | 0.397 (− 1.450 to 2.244) | 0.641 | − 0.053 (− 2.276 to 2.170) | 0.467 |
| Loss of appetite | − 0.570 (− 1.303 to 0.162) | 0.068 | − 0.571 (− 1.410 to 0.268) | 0.110 | − 1.058 (− 2.066 to − 0.049) | 0.040 |
| Constipation | − 1.088 (− 2.191 to 0.015) | 0.054 | − 1.020 (− 2.286 to 0.247) | 0.060 | − 1.144 (− 2.669 to 0.381) | 0.102 |
| Diarrhea | − 1.090 (− 1.788 to − 0.391) | 0.004 | − 1.220 (− 2.010 to − 0.431) | 0.003 | − 1.342 (− 2.292 to − 0.392) | 0.009 |
| Financial impact | 1.636 (0.309 to 2.963) | 0.031 | 1.212 (− 0.277 to 2.702) | 0.463 | 0.760 (− 1.032 to 2.552) | 0.992 |
Multivariate linear regressions were used to analyze the association of “vegetables and fruits pattern” and QoL. QoL items were log10 transformed in multivariate linear regressions, and the β values presented in the table were back-transformed to better interpret the results. The potential confounders were introduced in the models using the enter method. Model 1, adjusted for age at 18-month follow-up, education level, income status, total number of comorbidities, menopausal status at 18-month follow-up, AJCC stage, ER status and PR status, current usage of adjuvant hormonal therapy, BMI at 18-month follow-up, level of physical activity, total energy intake; Model 2, further adjusted for factor scores of “grain and animal food pattern”
B Unstandardized coefficient of linear regression model, 95%CI 95% confidence interval, QoL quality of life, EORTC QLQ-C30 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, AJCC American joint Committee on cancer, ER estrogen receptor, PR progesterone receptor
Bold face: P < 0.05