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. 2022 Apr 21;13(4):392. doi: 10.1038/s41419-022-04838-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A Heatmaps analysis on RNA expression of tumor and paired normal tissues from 87 Chinese GC patients. Samples are in columns, grouped by metastatic-potential and sample type (tumor or normal tissues). B Gene set enrichment analysis (GSEA) of gene signatures enrichment in HMP tumors vs. HMP normal tissues, but no enrichment in LMP tumors vs. LMP normal tissues. C–E Prognostic value and accuracy of the the integrated mRNA-lncRNA signature and traditional TNM stage in TCGA cohort. F The scores of 64 different cell types by xCell algorithm. G, H The scores of endothelial cells and M2 macrophage in different group. I Heatmaps analysis on mRNA expression for six types of immune-related genes: cytokines, cytokine receptors, immunotherapy targets, immunomodulators, stem cell markers, EMT markers.