Table 3.
Comparisons between the low SMI group and normal SMI group.
| Low SMI (n = 33) | Normal (n = 45) | P-value | |
|---|---|---|---|
| Male/female | 17/16 | 33/12 | 0.047 |
| Age (year), mean ± SD | 44.0 ± 14.6 | 41.6 ± 12.6 | 0.47 |
| BMI (kg/m2), mean ± SD | 18.8 ± 2.3 | 21.6 ± 3.2 | < 0.0001 |
| Height (cm), mean ± SD | 162.5 ± 8.5 | 167.8 ± 7.8 | 0.006 |
| Weight (kg), mean ± SD | 50.0 ± 8.8 | 61.0 ± 10.2 | < 0.0001 |
| CDAI, mean ± SD | 97.6 ± 59.5 | 93.4 ± 53.6 | 0.76 |
| Disease duration (year), mean ± SD | 15.9 ± 12.06 | 12.84 ± 8.57 | 0.21 |
| CRP (mg/dL), mean ± SD | 0.21 ± 0.31 | 0.39 ± 0.51 | 0.09 |
| ALB (g/dL), mean ± SD | 3.91 ± 0.56 | 3.92 ± 0.54 | 0.91 |
| IL-6 (pg/mL), mean ± SD | 2.69 ± 2.61 | 2.41 ± 2.07 | 0.6 |
| TNF-α (pg/mL), mean ± SD | 17.69 ± 20.45 | 28.63 ± 34.9 | 0.09 |
| GDF-8 (pg/mL), mean ± SD, | 4107.1 ± 1418.1 | 4244.9 ± 1558.2 | 0.7 |
| GDF-15 (pg/mL), mean ± SD | 1511.0 ± 1646.3 | 688.2 ± 575.3 | 0.013 |
Data was analyzed either by t test or χ2 test.
BMI body mass index, CDAI Crohn’s disease activity index, CRP C-reactive protein, ALB albumin, IL-6 Interleukin-6, TNF-α tumor necrosis factor-alpha, GDF-8 growth differentiation factor-8, GDF-15 growth differentiation factor-15, SD standard deviation, SMI skeletal muscle mass index.
Significant values are in bold.