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. 2022 Apr 21;12:6548. doi: 10.1038/s41598-022-10311-y

Table 6.

The modulation of the verapamil-stimulated (100 µM) P-glycoprotein ATPase activity by selected ketone-selenoesters.

Cpd IC50 [µM]
K3 11.7 ± 1.0a
K4 23.0 ± 0.2b
K7 25.7 ± 0.6c

Data are expressed as the average inhibitory concentration (IC50) of three repetitions with standard error of the mean (SEM). The statistical differences between compounds were calculated by one-way analysis of variance (ANOVA) and Duncan’s post hoc test (p ˂ 0.05), where significances were denoted by different letters (a–c).