Table 8.

Sensitization of resistant 3D ovarian (HOC/ADR) and breast (MCF-7/PAX) cancer spheroids by selected selenoesters.

Cpd	HOC/ADR		MCF-7/PAX
	Tested concentration [µM]	Fold change	Tested concentration [µM]	Fold change
K3	3	(1.2 ± 0.2)×	3	(0.9 ± 0.0)×
K4	5	(2.3 ± 0.1)×	3	(1.0 ± 0.1)×
K7	5	(1.6 ± 0.1)×	5	(1.1 ± 0.1)×

Data are expressed as the average sensitization rate (fold change) of four repetitions with standard error of the mean (SEM). Fold change was determined as the ratio of Adriamycin/paclitaxel IC₅₀ and Adriamycin/paclitaxel + selenoesters IC₅₀.