Figure 4.

CCR5mut T cells and macrophages resist SIV infection

(A and B) Fib-iPSC-derived mutant and WT T cells (A) and macrophages (B) were incubated with the T-cell-tropic SIVmac239 and macrophage-tropic SIVmac316, respectively. Virus production was measured by collecting cell culture supernatant on days 1, 4, and 7 post-infection and performing SIV Gag p27 ELISAs. The graph is representative of three independent experiments performed in triplicate. The error bars represent the SE of each time point. ^∗Denotes p < 0.05.