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. 2001 Jan;45(1):67–72. doi: 10.1128/AAC.45.1.67-72.2001

TABLE 4.

MICs and PAEs of five H. influenzae strains

Drug MIC range (μg/ml) PAE (h)a
ABT-773b 1.0–8.0 ≥6.1 (4.9–>8.0)
Erythromycinb 4.0–16.0 ≥3.8 (0.9–>6.7)
Azithromycinb 2.0–8.0 ≥6.1 (4.4–>7.4)
Clarithromycinb 4.0–16.0 ≥3.3 (1.6–>6.7)
Roxithromycinb 8.0–32.0 ≥3.3 (1.9–>6.7)
Amoxicillinb 0.5–4.0 0.5 (0–2.6)
Amoxicillin-clavulanateb 0.5–1.0 0.7 (0–3.4)
Cefuroximec 0.5–1.0 1.0 (0–5.0)
Cefiximec 0.016–0.125 0.7 (0–3.7)
Cefpodoximec 0.125–0.25 0.7 (0–3.5)
Cefprozild 4.0–16.0 0.7 (0–3.3)
Ceftriaxonec 0.004–0.008 0.6 (0–3.2)
a

Mean (range). 

b

Exposure at 4 times MIC for 1 h. 

c

Exposure at 10 times MIC for 1 h. 

d

Exposure at 2 times MIC for 1 h.