Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 8;12:855603. doi: 10.3389/fonc.2022.855603

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Wu, He, Xiong, Shi, Chen, Feng and Wen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

BH modulates the expression of multiple proteins. (A) Western bolt was used to detect the expression of cleaved caspase-3, caspase-3, Bcl-2, and Bax protein. (B) The protein levels of Notch3, β-catenin, FOXO3a, and EGFR in PC-9/GR cells treated with BH (4, 8 μM) and/or gefitinib (25 μM) for 24 h. (C, D) Immunofluorescent images of PC-9/GR cells represented the accumulation of FOXO3a. Scale bars, 50 μm. “*” represents Gef +BH group, BH group, Gef group vs. the Control group (*p < 0.05, **p < 0.01).