Table 2.
Dose (vg/dose) | 3.0 × 1013 | 3.3 × 1013 | 8.7 × 1013 |
---|---|---|---|
Number of injections | 1 | 3 | 1 |
n per group | 2 | 2 | 2 |
Neuron degeneration/necrosis | 0 | 1 | 2 |
Minimal (Grade 1) | 0 | 0 | 0 |
Mild (Grade 2) | 0 | 1 | 1 |
Moderate (Grade 3) | 0 | 0 | 1 |
Nerve fiber degeneration | 0 | 1 | 2 |
Minimal (Grade 1) | 0 | 1 | 1 |
Mild (Grade 2) | 0 | 0 | 0 |
Moderate (Grade 3) | 0 | 0 | 1 |
Mononuclear cell infiltration | 2 | 1 | 2 |
Minimal (Grade 1) | 2 | 0 | 0 |
Mild (Grade 2) | 0 | 1 | 1 |
Moderate (Grade 3) | 0 | 0 | 1 |