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. 2022 Apr 18;14(4):841. doi: 10.3390/v14040841

Figure 4.

Figure 4

Proposed model for the antiviral mechanism of molnupiravir based on β-d-N4-hydroxycytidine (NHC)-induced mutagenesis and the inhibition of RNA synthesis. Tautomeric forms and the base pairing of NHC are shown in the lower-left panel. Illustration based on the experimental data reported by Gordon et al. [136] and Kabinger et al. [137], and adapted from ref. [146].