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. 2022 Apr 1;9(4):491. doi: 10.3390/children9040491

Table 5.

Disease severity according to age. CPAP, continuous positive airway pressure; HFNC, high-flow nasal cannulae; PICU, pediatric intensive care unit.

216 Patients with an Identified Virus 12 Months or Less
n = 193
>12 Months
n = 23
p-Value
RSV, n (%) 147 (76.17) 15 (65.22) 0.25
Rhinovirus, n (%) 38 (19.69) 10 (43.48) 0.009
SARS-CoV-2, n (%) 18 (9.33) 0 0.12
Human-Metapneumovirus, n (%) 11 (5.70) 1(4.35) 0.79
Parainfluenza, n (%) 9 (4.66) 0 0.36
Adenovirus, n (%) 1 (0.50) 1 (4.35) 0.2
Other viruses, n (%) 8 (4.15) 6 (26.09) 0.001
Coinfection, n (%) 37 (19.17) 6 (26.9) 0.294
657 total patients 12 months or less
n = 548
>12 months
n = 109
p-Value
Admitted to hospital, n (%) 315 (57.48) 53 (48.62) 0.09
Admitted to PICU, n (%) 21 (3.83) 5 (4.59) 0.72
Admitted to PICU within the first 7 days since initial evaluation, n (%) 34 (6.20) 5 (4.59) 0.34
Need for High Flow Oxygen *, n (%) 148 (27.01) 19 (17.43) 0.04
CPAP *, n (%) 35 (6.39) 8 (7.34) 0.71
Mechanical ventilation *, n (%) 1 (0.18) 1 (0.92) 0.3

* Calculated if anytime needed within the first seven days since the initial hospital evaluation.