Table 6.
Disease severity according to gestational age. CPAP, continuous positive airway pressure; HFNC, high-flow nasal cannulae; PICU, pediatric intensive care unit.
| 214 CHILDREN with a Virus Isolated and Known Gestational Age | <34 Weeks n = 8 |
34–36 Weeks n = 19 |
37 or More n = 187 |
p-Value |
|---|---|---|---|---|
| RSV, n (%) | 6 (75.00) | 13 (68.42) | 142 (75.94) | 0.77 |
| Rhinovirus, n (%) | 2 (25.00) | 5 (26.32) | 40 (21.39) | 0.65 |
| SARS-CoV-2, n (%) | 0 | 2 (10.53) | 16 (8.56) | 0.84 |
| Human-Metapneumovirus, n (%) | 1 (12.50) | 0 | 11 (5.88) | 0.39 |
| Parainfluenza, n (%) | 1 (12.50) | 2 (10.53) | 6 (3.21) | 0.1 |
| Adenovirus, n (%) | 0 | 0 | 2 (1.07) | 1 |
| Other viruses, n (%) | 2 (25.00) | 0 | 12 (6.42) | 0.08 |
| Coinfection, n (%) | 4 (50.00) | 3 (15.79) | 36 (19.46) | 0.11 |
| 636 children with known gestational age |
<34 weeks
n = 18 |
34–36 weeks
n = 42 |
37 or more
n = 576 |
p-Value |
| Admitted to hospital, n (%) | 15 (83.33) | 25 (59.52) | 316 (54.86) | 0.05 |
| Admitted to PICU, n (%) | 2 (11.11) | 1 (2.38) | 20 (3.47) | 0.19 |
| Admitted to PICU within the first 7 days since initial evaluation, n (%) | 3 (16.67) | 1 (2.38) | 33 (5.73) | 0.1 |
| Need for High Flow Oxygen *, n (%) | 7 (38.89) | 13 (30.95) | 105 (18.23) | 0.015 |
| CPAP *, n (%) | 3 (16.67) | 3 (7.14) | 35 (6.08) | 0.168 |
| Mechanical ventilation *, n (%) | 1 (5.56) | 0 | 1 (0.17) | 0.06 |
* Calculated if anytime needed within the first seven days since the initial hospital evaluation.