Table 1.
Comparison the LODs and test ranges for various immunosensing methods for Vtg/Lv detection.
| No | Sensors Type | Antibody Type | LOD (ng/mL) |
Linear Range (ng/mL) |
Reference |
|---|---|---|---|---|---|
| 1 | Electrochemical impedance sensor | mAb | 42 | 1000.0–8000.0 | [46] |
| 2 | Amperometric sensor | mAb | 0.09 | 0.25–7.8 | [47] |
| 3 | Optical surface plasmon resonance | mAb | 1000 | 1000–10,000 | [48] |
| 5 | Optical waveguide lightmode spectroscopy | polyAb | 300(direct) 0.07(indirect) |
600–12,000 a 3–100 b |
[51] |
| 6 | Surface-enhanced Raman scattering | polyAb | 0.005 | <0.2 c | [49] |
| 7 | Optical waveguide lightmode spectroscopy | polyAb | Data not show | 100–10,000 b 0.5–50 c |
[50] |
| 8 | ELISA d | polyAb | Data not show | 7.8–250 | [55] |
| 9 | ELISA d | mAb | 0.75 | 1.95–250 | [56] |
| 10 | FRET sensor | mAb | 0.009 | 0.001–1500 | This study |
a: Direct manner, antibody was immobilized on the sensor surface. b: Indirect manner, competitive measurement, Lv was applied for the immobilization. c: Data not shown, judging from the result. d: Sandwich enzyme-linked immunosorbent assay. mAb = Monoclonal antibody; pAb = Polyclonal antibody.