Table 6.
The docking scores of sofosbuvir with the 10 models of HCV GT4a NS5B.
Sample No. | Docking Score (KCal/Mole) |
---|---|
Sample 1 (resistant) | –16.5 |
Sample 2 (resistant) | –17.3 |
Sample 3 (resistant) | –15.8 |
Sample 4 (resistant) | –17.4 |
Sample 5 (resistant) | –16.2 |
Sample 6 (responder) | –22.7 |
Sample 7 (responder) | –21.9 |
Sample 8 (responder) | –22.3 |
Sample 9 (responder) | –22.9 |
Sample 10 (responder) | –23.6 |