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. 2022 Apr 15;23(8):4391. doi: 10.3390/ijms23084391

Figure 7.

Figure 7

Phosphorous dendrimers prevent NMDA-mediated excitotoxicity in human brain organoids. Brain organoids were treated with either vehicle (V) or G4 phosphorous dendrimers (10 µM) for 1 h, and then NMDA (150 µM) was added and and incubation continued for another 24 h. LDH was determined as indicated in the Materials and Methods section. The data represent the mean ± the s.e.m. of six experiments. ** p < 0.01 when compared to NMDA-treated neurons in the absence of dendrimers.