TABLE 2.
Characterization and origin of 40 isolates of N. gonorrhoeae used in the study
| Strainc | β-Lactamase production | MIC (μg/ml)d of:
|
Size of β-lactamase coding plasmid (kb)e | Place of acquisition | |||
|---|---|---|---|---|---|---|---|
| CIP | PEN | CRO | TET | ||||
| 31/95 | + | 16 | >4 | 0.008 | ≤4 | 7.2 | Far East |
| 76/95 | + | 8 | >4 | 0.008 | ≤4 | 4.9 | Philippines |
| 81/95 | + | 8 | >4 | 0.004 | ≤4 | 4.9 | Thailand |
| 86/95 | − | 8 | 1 | 0.008 | ≤4 | Unknown | |
| 121/95* | + | 8 | >4 | 0.004 | ≤4 | 4.9 | Thailand |
| 128/95* | + | 8 | >4 | 0.004 | ≤4 | 4.9 | Thailand |
| 139/95 | + | 8 | >4 | 0.004 | ≤4 | 7.2 | Philippines |
| 152/95 | + | 8 | >4 | 0.064 | ≤4 | 5.1 | Thailand |
| 160/95† | − | 8 | 0.5 | 0.004 | ≤4 | PRCf | |
| 165/95† | − | 8 | 0.5 | 0.008 | ≤4 | PRC | |
| 169/95 | + | 8 | >4 | 0.002 | ≤4 | 4.9 | Unknown |
| 181/95 | + | 8 | >4 | 0.008 | ≤4 | 4.9 | Hong Kong |
| 253/95 | + | 16 | >4 | 0.002 | ≤4 | 4.9 | Thailand |
| 66/96 | + | 8 | >4 | 0.004 | 2 | 4.9 | Thailand |
| 72/96 | + | 8 | >4 | 0.008 | 4 | 4.9 | Philippines |
| 80/96‡ | + | 8 | >4 | 0.016 | 4 | 4.9 | Philippines |
| 88/96‡ | + | 8 | >4 | 0.008 | 4 | 4.9 | Philippines |
| 109/96 | + | 8 | >4 | 0.016 | 4 | 7.2 | Philippines |
| 110/96 | + | 8 | >4 | 0.008 | 4 | 4.9 | Philippines |
| 135/96 | − | 8 | 1 | 0.008 | 4 | Philippines | |
| 21/97 | + | 8 | >4 | 0.002 | 1 | 4.9 | Thailand |
| 24/97 | + | 8 | >4 | <0.001 | 1 | 5.1 | Thailand |
| 41/97 | − | 8 | 2 | 0.031 | 4 | Unknown | |
| 125/97 | + | 8 | >4 | 0.004 | 0.5 | 4.9 | Iraq |
| 134/97 | − | 32 | 0.5 | 0.004 | 4 | India | |
| 137/97 | + | 8 | >4 | 0.016 | 4 | 4.9 | Rumania |
| 163/97 | + | 8 | >4 | 0.016 | 4 | 4.9 | Denmark |
| 165/97 | + | 8 | >4 | 0.008 | 4 | 4.9 | New Guinea |
| 167/97a | + | 8 | >4 | 0.016 | 4 | 4.9 | Denmark |
| 176/97a | + | 8 | >4 | 0.016 | 8 | 4.9 | Denmark |
| 56/98 | − | 4 | 4 | 0.031 | 4 | Unknown | |
| 63/98 | − | 8 | 1 | 0.016 | 4 | PRC | |
| 88/98 | − | 4 | 0.5 | 0.004 | 1 | Unknown | |
| 105/98 | − | 16 | 2 | 0.016 | 4 | Unknown | |
| 182/98b§ | − | 4 | 1 | 0.016 | 2 | Denmark | |
| 193/98§ | − | 4 | 1 | 0.016 | 2 | Denmark | |
| 186/98 | − | 8 | 2 | 0.016 | 4 | Unknown | |
| 183/98∥ | − | 4 | 2 | 0.016 | 2 | Poland | |
| 194/98∥ | − | 4 | 2 | 0.016 | 2 | Poland | |
| 202/98 | + | 8 | >4 | 0.008 | 2 | 7.2 | Philippines |
a
Strain from a patient known to have contact with the source of strain 165/97.
b
Strain from a female patient known to have contact with the source of strain 183/98.
c
Pairs of isolates from patients are indicated by identical symbols.
d
CIP, ciprofloxacin; PEN, penicillin; CRO, ceftriaxone; TET, tetracycline.
e
7.2 kb, Asian type plasmid; 5.1 kb, African type plasmid; 4.9 kb, Toronto type plasmid.
f
PRC, People's Republic of China.