ADT	Androgen deprivation therapy
AR	Androgen receptor
ARKO	Androgen receptor knock-out
ARO	Cyp19A1 (aromatase)
BCT	Bicalutamide
BPH	Benign prostate hyperplasia
cAMP	Cyclic adenosine monophosphate
cGMP	Cyclic guanosine monophosphate
CRPC	Castration-resistant prostate cancer
E2	Estradiol
ED	Erectile dysfunction
ERα	Estrogen receptor alpha
ERβ	Estrogen receptor beta
LnCaP	Androgen-sensitive human PCa cell line
LUTS	Low urinary tract symptoms
NO	Nitric oxide
NO-cGMP-PKG	Nitric oxide-cyclic guanosine monophosphate-dependent protein kinase G
PCa	Prostate cancer
PDE	Phosphodiesterase
PDE5	Type-5 phosphodiesterase
PDE5i	Type-5 phosphodiesterase inhibitors
SAOS-2	Sarcoma osteogenic cell line (human osteoblasts)
T	Testosterone
T/E2	Testosterone/estradiol ratio