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. 2022 Apr 11;12(4):568. doi: 10.3390/life12040568

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Methodology. (a) The Early Treatment Diabetic Retinopathy Study (ETDRS) grid 1, 2.22, 3.45 mm, consisting of nine subfields (C0: center; S1 and S2 superior, N1 and N2 nasal, I1 and I2 inferior, and T1 and T2 temporal). Macular segments (b) are separated semi-automatically by the optical coherence tomography (OCT) software: nerve fiber layer (NFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), and retinal pigment epithelium (RPE). OCT-angiography example of the superficial (c) and deep (d) capillary plexus of the macula; the orange line indicates the borders of foveal avascular zone.