TABLE 1.
Susceptibilities of Aspergillus species conidia to voriconazole and itraconazole
| Aspergillus sp.a (no. of isolates tested) | Antifungal agent | MFC (μg/ml)
|
|
|---|---|---|---|
| Range | 50% | ||
| A. flavus (5) | Voriconazole | 0.5–2 | 1 |
| Itraconazole | 0.5–1 | 0.5 | |
| A. terreus (5) | Voriconazole | 0.5–1 | 0.5 |
| Itraconazole | 0.5–1 | 1 | |
| A. niger (5) | Voriconazole | 1–4 | 1 |
| Itraconazole | 1–2 | 1 | |
| A. fumigatus (5) | Voriconazole | 0.5–1 | 0.5 |
| Itraconazole | 025–1 | 0.5 | |
| Itraconazole-resistant A. fumigatus (1) | Voriconazole | 0.5–1 | 0.5 |
| Itraconazole | >16 | NDb | |
a
Each isolate was tested three times.
b
ND, not determined.