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. 2022 Apr 11;11(4):756. doi: 10.3390/antiox11040756

Figure 5.

Figure 5

Astroglial GPx1 expression in the stratum radiatum (SR) of the CA1 region following SE. GPx1 expression is reduced at 1 day and 3 days after SE, but upregulated in reactive CA1 astrocytes of chronic epilepsy rats. GPx1 expression is rarely detected in clasmatodendritic CA1 astrocytes (arrows). (A) Representative photos of GPx1 expression and its intensity. Bar = 12.5 μm. (B) Quantification of GPx1 intensity in CA1 astrocytes (*,# p < 0.05 vs. control and 3 day-post SE animals, n = 7, respectively). (C) Representative photos of clasmatodendritic CA1 astrocytes containing lysosome-associated membrane protein 1 (LAMP1)-positive vacuoles (arrows). Insertions are high magnification of rectangles. Bar = 25 and 12.5 μm (insertion).