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. 2022 Apr 1;8(2):961–973. doi: 10.3390/tomography8020077

Table 1.

Main PMCT and PMCTA findings and comparison to autopsy and histology findings from the reviewed works.

Author Cases Analyzed Main Findings
Michaud et al. [2] 23
  • -

    Calcifications detected in 18/23 cases on both PMCT and PMCTA, 12 of which correspond to thrombosis at autopsy;

  • -

    In total, 50–75% stenosis detected in 1/23 case on PMCTA, corresponding to an eroded plaque-related thrombosis at histology;

  • -

    In total, 75% stenosis of the LAD detected in 1/23 case on both PMCT and PMCTA, confirmed at both autopsy and histology;

  • -

    Thrombosis detected in 14/23 cases at autopsy, corresponding—on PMCTA—to 11 non-perfused segments and 2 partial occlusions in non-calcified coronary arteries.

Singh et al. [7] 37
(158 sections)
Critical stenosis:
  • -

    In total, 20 cases on PMCTA;

  • -

    In total, 13 cases at histology;

  • -

    Agreement in 8 cases.

Sensitivity 61.5%; Specificity 91.7%; PPV 40%; NPV 96.4%.
Morgan et al. [14] 5
(25 vessels;
568 sections)
  • -

    Calcifications detected in 49 sections on PMCTA, with agreement at histology in 39 cases;

  • -

    Mild to critical stenosis detected in 124 sections at histology, with agreement on PMCTA in 101 cases.

Sensitivity 50%; Specificity 92%; PPV 50%; NPV 92%.
Further evidence, at histology, of: plaque hemorrhage in 5 sections; plaque dissection in 3 sections; and recanalization in 5 sections.
Turillazzi et al. [16] 2 Case 1:
  • -

    LCx calcification detected on MPMCT;

  • -

    LCX thrombosis and advanced atherosclerotic plaque detected at histology but not on MPMCTA;

  • -

    Myocardial infarction detected at histology but not on PMCTA.

Case 2:
  • -

    LAD calcification detected on MPMCT, corresponding to wall thickening on MPMCTA and atherosclerotic plaque at histology;

  • -

    RCA diffuse narrowing detected on MPMCTA;

  • -

    Myocardial infarction detected at histology but not on PMCTA.

Polacco et al. [17] 11
  • -

    Contrast media extravasation in the wall of the left ventricular myocardium detected on PMCTA in 7/11 cases, 6 of which correspond to the distribution area of an affected (stenotic or abnormal) coronary artery; 1/7 case, false positive;

  • -

    Infarcted area detected in 1/11 case at both autopsy and histology but not on PMCTA (false negative).

Wan et al. [21] 1
  • -

    Severe calcification of the LAD on PMCT, corresponding to a 50–75% stenosis on PMCTA and to coronary atherosclerosis at histology;

  • -

    Diffuse calcification of LCx and RCA on PMCT, corresponding to a 50% stenosis on PMCTA and to coronary atherosclerosis at histology;

  • -

    Acute myocardial ischemic changes detected at histology but not at autopsy, PMCT or PMCTA.

Lee et al. [22] 1
  • -

    Thrombosis of the distal segment of the RCA detected on PMCTA;

  • -

    Transmural contrast defect involving the RCA territory, confirmed as infarcted area at both autopsy and histology.