Effect of Camu-Camu on hepatic metabolism in DIO mice. Effects of oral administration of vehicle or CCE in 6-hour-fasted mice after 5 weeks of treatment on (A) liver weight, (B) liver triglycerides, and (C) cholesterol content and the gene expression of hepatic biomarkers involved in (D) fatty acid oxidation (no significant difference was observed), (E) fatty acid synthesis, (F) endocrine signaling (no significant difference was observed), (G) inflammation (no significant difference was observed); n = 9–10 per group. In figure (B–D), data with different superscript letters are significantly different (p < 0.05) according to post hoc ANOVA one-way statistical analysis (Bonferroni’s post hoc test).