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. 2022 Apr 8;12(4):551. doi: 10.3390/biom12040551

Table 5.

Factors associated with all-cause and cardiovascular mortality in peritoneal dialysis patients.

Multivariate Cox Regression Analysis
All-Cause Mortality Cardiovascular Mortality
Variable: p HR 95% CI p HR 95% CI
Model 1: OPG (pmol/L) 0.002 a 1.08 1.03 1.14 0.013 b 1.09 1.02 1.66
   Alb (g/dL) 0.012 b 0.35 0.15 0.79 0.194 0.45 0.13 1.50
    cCa (mg/dL) 0.353 1.13 0.87 1.46 0.001 a 1.53 1.19 1.98
   VC (CaSc) 0.616 1.00 1.00 1.00 0.163 1.00 1.00 1.00
   P (mg/dL) 0.445 1.11 0.85 1.44 0.691 0.91 0.59 1.40
     PTH (pg/mL) 0.297 1.00 0.99 1.01 0.030 b 1.00 1.00 1.01
      LnCRP(mg/L) 0.090 1.29 0.96 1.74 0.092 1.45 0.94 2.25
Model 2:  Model 1 + DM
     OPG (pmol/L) 0.040 1.06 1.00 1.12 0.279 1.05 0.96 1.13
   Alb (g/dL) 0.054 0.43 0.182 1.05 0.385 0.58 0.17 1.98
    cCa (mg/dL) 0.231 1.17 0.90 1.53 0.001 a 1.65 1.25 2.17
   VC (CaSc) 0.791 1.00 1.00 1.00 2.242 1.00 1.00 1.00
   P (mg/dL) 0.353 1.41 0.86 1.50 0.843 0.96 0.62 1.48
     iPTH (pg/mL) 0.154 1.002 0.99 1.00 0.008 b 1.00 1.00 1.01
     Ln CRP (mg/L) 0.069 1.32 0.97 1.79 0.060 1.54 0.982 2.415
   DM (yes) 0.087 0.343 0.101 1.16 0.054 7.14 0.966 52.786
Model 3:  Model 2 + Age
     OPG (pmol/L) 0.127 1.048 0.987 1.112 0.409 1.03 0.954 1.124
   Alb (g/dL) 0.042 b 0.411 0.174 1.53 0.155 0.420 0.127 1.389
    cCa (mg/dL) 0.225 1.181 0.903 1.544 0.001 a 1.67 1.25 2.219
   VC (CaSc) 0.819 1.00 1.00 1.00 0.190 1.00 1.00 1.00
   P (mg/dL) 0.252 1.18 0.89 1.56 0.891 0.970 0.624 1.508
     iPTH (pg/mL) 0.225 1.18 0.90 1.54 0.012 b 1.01 1.00 1.009
     lnCRP (mg/L) 0.074 1.32 0.97 1.79 0.079 1.51 0.954 2.393
   DM (yes) 0.321 0.51 0.13 1.93 0.300 3.14 0.361 27.21
  Age (y) 0.227 1.03 0.98 1.08 0.030 b 1.08 1.007 1.159

Model 1 shows multivariable analysis with calcium metabolism biomarkers. Model 2 shows and adds DM to Model 1 plus DM. Model 3 shows and adds age to Model 1 plus DM and age2. Significance = a p < 0.005, b p < 0.05.