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. 2022 Mar 28;14(4):723. doi: 10.3390/pharmaceutics14040723

Table 1.

Patient demographics and baseline characteristics.

Patient Characteristics 62 Eyes (46 Patients)
Mean age, years (SD) 71.6 (8.9)
Sex Female, n (%) 25 (54.3)
Mean DM duration, years (SD) 25.0 (12.1)
DM type, n (%)
Type 1
Type 2

7 (15.2)
39 (84.8)
Mean DME duration, months (SD) 60.3 (30.6)
Mean follow-up duration, months (SD)
Eyes followed, n (%)
>6 months
>12 months
>18 months
>24 months
13.9 (7.5)

50 (80.6)
38 (61.3)
24 (38.7)
4 (0.6)
Mean baseline IOP, mmHg (SD) 13.4 (2.7)
Mean HbA1c, % (SD) 7.9 (1.3)
Pseudophakic eyes, n (%) 60 (96.8)
History of vitrectomy, n (%) 18 (29.0)
Bilateral Fac injections, n (%) 16 (34.8)
Mean baseline BCVA, ETDRS letters (SD) 64.0 (17.2)
Mean baseline CMT, µm (SD) 333.3 (112.5)
Mean number of previous intravitreal injections, n (SD) 16.0 (9.1)
Anti-VEGF
Ranibizumab
Aflibercept
Bevacizumab
9.2 (6.0) in 52 eyes (83.9%)
6.4 (4.8) in 32 eyes (51.6%)
6.4 (3.7) in 42 eyes (67.7%)
2.0 (0.0) in 3 eyes (5%)
Corticosteroids
Dexamethasone
Triamcinolone
8.2 (4.4) in 62 eyes (100%)
8.2 (4.2) in 62 eyes (100%)
2.25 (1.0) in 4 eyes (6.5%)
Laser, n (%):
All
Focal
PRP
Focal and PRP

47 (75.8)
18 (29.0)
45 (72.6)
16 (25.8)
Baseline IOP-lowering therapy, n (%)
None
Monotherapy
Dual therapy
>Dual therapy
History of IOP-lowering surgery
Previous SLT

41 (66.1)
11 (17.7)
10 (16.1)
0
1 (1.6)
5 (8.1)

BCVA: best corrected visual acuity; CMT: central macular thickness; DM: diabetes mellitus; DME: diabetic macular edema; ETDRS: early treatment diabetic retinopathy study; IOP: intraocular pressure; PRP: panretinal photocoagulation; SD: standard deviation; SLT: selective laser trabeculoplasty.