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Scheme of the investigation. RT-qPCR, reverse transcription polymerase chain reaction; ELISA, enzyme-linked immunosorbent assay; Eng, endoglin; VEGFA, vascular endothelial growth factor A; VEGFR1, vascular endothelial growth factor receptor 1 (or FLT1); VEGFR2, vascular endothelial growth factor receptor 2 (or FLK), HIF1A, hypoxia-inducible factor 1A. Note: FLT1 and FLK were not determined in the samples of distal veins.
