Table 2.
Expression (%) of the genes investigated in samples of the proximal internal saphenous vein.
| Primary Varicose Veins | Recurrent Varicose Veins | ||||||
|---|---|---|---|---|---|---|---|
| Genes * | Mean | SD | SEM | Mean | SD | SEM | p-Value |
| Eng | 100 | 77.65 | 16.94 | 149.8 | 75.29 | 17.75 | 0.0104 |
| HIF1A | 100 | 44.14 | 96.32 | 97.28 | 43.94 | 10.38 | 0.8554 |
| VEGFA | 100 | 50.13 | 10.94 | 173.0 | 104.1 | 24.54 | 0.0074 |
| VEGFR1 | 100 | 88.50 | 19.31 | 287.7 | 186.3 | 43.91 | < 0.0001 |
| VEGFR2 | 100 | 80.37 | 17.54 | 346.4 | 255.1 | 60.13 | < 0.0001 |
* Genes investigated: Eng, endoglin; HIF1A, hypoxia-inducible factor 1A; VEGFA, vascular endothelial growth factor A; VEGFR1, vascular endothelial growth factor receptor 1 (FLT1); VEGFR2, vascular endothelial growth factor receptor 2 (FLK).