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Median and 5th to 95th percentiles of individual pharmacokinetic parameters (post hoc estimates) for acyclovir after oral administration
| Value | CL/F (liters/h) | CL/F (liters/h/kg) | CL/F (liters/h/m2) | V/F (liters) | V/F (liters/kg) | V/F (liters/m2) | ka (h−1) |
|---|---|---|---|---|---|---|---|
| Median | 20.9 | 3.1 | 56.3 | 37.3 | 5.4 | 93.2 | 0.28 |
| 5th to 95 percentile | 1.7–93.9 | 0.6–9.8 | 7.5–201 | 12.1–81.4 | 3.5–8.2 | 54.1–170 | 0.28–0.28 |
| CV (%) | 98 | 79 | 86 | 53 | 27 | 31 |
