. 2022 Apr 3;10(4):556. doi: 10.3390/vaccines10040556

Table 3.

Decline rate of the NAb percentage inhibition against the WT, Delta and Omicron variant over time and Median Fold Change of percentage inhibition of NAb on day 30 and day 90 between the Delta and Omicron variants.

		CoronaVac Group (n = 98)	Decline Rate	Fold Change	BNT162b2 Group (n = 136)	Decline Rate	Fold Change
NAb Median percentage inhibition against WT	Day 30	87.9 (63.6–97.7) n = 92	Day 30 to 90: −23.5%		99.5 (99.3–99.6) n = 130	Day 30 to 90: 0.0%
NAb Median percentage inhibition against WT	Day 90	67.2 (35.2–86.5) n = 77	Day 30 to 90: −23.5%		99.5 (98.7–99.6) n = 126	Day 30 to 90: 0.0%
NAb Median percentage inhibition against Delta	Day 30	78.2 (44.6–94.1) n = 92	Day 30 to 90: −36.4%	Delta Day 30 vs. Omicron Day 30: 35.5	99.1 (98.3–99.3) n = 130	Day 30 to 90: −0.3%	Delta Day 30 vs. Omicron Day 30: 1.8
NAb Median percentage inhibition against Delta	Day 90	49.7 (26.8–80.2) n = 77	Day 30 to 90: −36.4%	Delta Day 30 vs. Omicron Day 30: 35.5	98.8 (93.6–99.4) n = 126	Day 30 to 90: −0.3%	Delta Day 30 vs. Omicron Day 30: 1.8
NAb Median percentage inhibition against Omicron	Day 30	2.2 (0–18.2) n = 92	Day 30 to 90: 218.2% *	Delta Day 90 vs. Omicron Day 90: 7.1	56.4 (20.9–75.9) n = 130	Day 30 to 90: −48.4%	Delta Day 90 vs. Omicron Day 90: 3.4
NAb Median percentage inhibition against Omicron	Day 90	7 (0–14.4) n = 77	Day 30 to 90: 218.2% *	Delta Day 90 vs. Omicron Day 90: 7.1	29.1 (4.2–50.1) n = 126	Day 30 to 90: −48.4%	Delta Day 90 vs. Omicron Day 90: 3.4

* most samples are negative for NAb and the median percentage inhibition is not representative of the natural decline. Median and p-values were tested using a Mann-Whitney test (By Prism GraphPad Software).