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T2-weighted MRI results of orthotopic breast tumor before and after i.v. administration of MTN with corresponding treatments: MTN (A1–A3) and MTN + MT (B1–B3). Before intravenous injection of MTN, orthotopic breast tumors were scanned by MRI as control (A1,B1). After injection, the duration time of MT was 4 h, and the tumors were scanned again at 20 h (A2,B2). After MH of 20 min, the third MRI results (A3,B3) were obtained at 22 h after intravenous injection of MTN.
