Table 3.
Factors associated with the development of major complications and PHLF B or C after hepatic resection for HCC.
| Major Complications | PHLF B or C | |||
|---|---|---|---|---|
| Variables | Univariate Analysis | Univariate Analysis | ||
| OR (95%-CI) | p-Value | OR (95%-CI) | p-Value | |
| Age | 0.974 (0.926–1.026) |
0.322 | 0.980 (0.933–1.030) |
0.432 |
| Sex (male) | 1.363 (0.286–6.491) |
0.697 | 0.577 (0.168–1.979) |
0.382 |
| BMI (kg/m2) | 1.037 (0.895–1.201) |
0.631 | 0.890 (0.760–1.041) |
0.146 |
| Diabetes mellitus | 2.271 (0.720–7.170) |
0.162 | 0.971 (0.289–3.271) |
0.963 |
| LSM > 10 kPa (n = 108) | 2.660 (0.512–13.822) |
0.244 | 13.565 (1.705–107.907) |
0.014 |
| Thrombocytopenia | 1.011 (0.329–3.154) |
0.985 | 4.849 (1.297–18.127) |
0.019 |
| Esophageal varices (n = 154) | 0.429 (0.091–1.740) |
0.284 | 2.757 (0.906–8.391) |
0.074 |
| Portal hypertension | 0.598 (0.191–1.868) |
0.376 | 3.384 (1.076–10.642) |
0.037 |
| MELD score | 1.211 (1.018–1.442) |
0.031 | 1.144 (0.962–1.360) |
0.127 |
| Child-Pugh score | 2.050 (0.684–2.159) |
0.085 | 2.218 (1.008–4.883) |
0.048 |
| ALBI score | 1.981 (0.715–5.488) |
0.188 | 7.195 (2.171–23.844) |
0.001 |
| Major hepatectomy | 0.884 (0.231–3.385) |
0.857 | 0.818 (0.216–3.097) |
0.768 |
| Sarcopenia (dichotomous) | 1.557 (0.486–4.983) |
0.453 | 1.751 (0.559–5.479) |
0.336 |
| SMI (continuous) | 0.975 (0.918–1.036) |
0.410 | 0.972 (0.917–1.032) |
0.362 |
ALBI: albumin-bilirubin score; BMI: body mass index; CI: confidence interval; HCC: hepatocellular carcinoma; LSM: liver stiffness measurement; MELD: Model for end-stage-liver-disease; OR: odds ratio; PHLF: post-hepatectomy liver failure; SMI: skeletal muscle index.