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. 2022 Mar 25;11(4):629. doi: 10.3390/antiox11040629

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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HOFE (100 μg/mL) effect on Aβ-induced paralysis CL4176 nematodes. (A) Paralysis curve. For each time, different letters represent statistically significant differences (p < 0.05) between groups. Results are expressed as mean ± SEM. (B) Typical images from each experimental group presenting Thioflavin T aggregates in worms at 26 h after temperature shifting (40× magnification). Aβ aggregates are indicated with white arrows. Negative control is represented by the non-paralyzable strain CL802. Positive control is the non-treated CL4176.