Table 1.
Antibiotic consumption during indicated period in hospitalized patients.
| Ward | ICU | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Antibiotics | Hospital | March 2018 –September 2019 |
March 2020 –September 2021 |
% Change | p | March 2018 –September 2019 |
March 2020 –September 2021 |
% Change | p |
|
Penicillin
with β-lactamase inhibitors |
Total | 72.48 | 74.97 | +3.4 | <0.001 | 115.78 | 122.53 | +5.8 | <0.001 |
| A | 69.60 | 106.17 | +52.5 | <0.001 | 195.13 | 258.44 | +32.4 | <0.001 | |
| B | 32.07 | 28.65 | −10.7 | <0.001 | 23.44 | 22.79 | −2.8 | <0.001 | |
| C | 75.37 | 72.71 | −3.5 | 0.385 | 124.60 | 125.42 | +0.7 | 0.847 | |
| D | 95.91 | 100.43 | +4.7 | <0.001 | 170.19 | 185.46 | +9.0 | <0.001 | |
| Vancomycin | Total | 11.58 | 13.52 | +16.7 | <0.001 | 49.35 | 47.37 | −4.0 | <0.001 |
| A | 6.01 | 9.48 | +57.8 | <0.001 | 86.82 | 86.80 | −0.0 | 0.024 | |
| B | 9.62 | 8.67 | −9.9 | <0.001 | 33.16 | 33.56 | +1.2 | 0.016 | |
| C | 14.25 | 14.50 | +1.8 | <0.001 | 71.99 | 63.51 | −11.8 | 0.982 | |
| D | 12.52 | 16.75 | +33.7 | <0.001 | 32.41 | 37.38 | +15.3 | <0.001 | |
| Carbapenems | Total | 30.15 | 37.96 | +25.9 | <0.001 | 123.99 | 139.00 | +12.1 | <0.001 |
| A | 14.72 | 6.39 | −56.6 | <0.001 | 163.53 | 120.45 | −26.3 | <0.001 | |
| B | 19.68 | 26.77 | +36.0 | <0.001 | 95.24 | 127.94 | +34.3 | <0.001 | |
| C | 42.16 | 58.30 | +38.3 | <0.001 | 195.83 | 182.31 | −6.9 | <0.001 | |
| D | 32.42 | 36.39 | +12.2 | <0.001 | 77.99 | 111.57 | +43.1 | <0.001 | |
Values for antibiotic consumption are presented as DDDs/1000 patient-days. Data are compared using the Pearson’s chi-square test or Fisher’s exact test. ICU, intensive care unit.