Table 3.
In female fetuses, alcohol exposure reduced absolute fetal and organ weights and increased relative weights of brain and heart.
FEMALES | p Value | ||||||
---|---|---|---|---|---|---|---|
CON | ALC | CON + Iron | ALC + Iron | ALC | Iron | ALC × Iron | |
Absolute weight (g) | |||||||
Fetus | 3.52 ± 0.30 a | 2.88 ± 0.41 b | 3.46 ± 0.27 a | 2.94 ± 0.48 b | <0.001 | 0.819 | 0.562 |
Placenta | 0.37 ± 0.07 | 0.34 ± 0.04 | 0.35 ± 0.05 | 0.32 ± 0.04 | 0.163 | 0.322 | 0.809 |
Brain | 0.16 ± 0.02 a | 0.14 ± 0.01 b | 0.15 ± 0.02 ab | 0.15 ± 0.01 b | 0.044 | 0.518 | 0.062 |
Liver | 0.27 ± 0.05 a | 0.20 ± 0.04 b | 0.25 ± 0.03 a | 0.21 ± 0.04 b | <0.001 | 0.588 | 0.293 |
Heart | 0.016 ± 0.003 a | 0.015 ± 0.002 c | 0.016 ± 0.002 ab | 0.015 ± 0.003 bc | 0.019 | 0.624 | 0.607 |
Placental efficiency | 9.73 ± 1.51 ab | 8.69 ± 1.25 c | 10.11 ± 1.21 a | 9.04 ± 1.35 bc | 0.006 | 0.327 | 0.894 |
Relative weight (g/100 g total body weight) | |||||||
Brain | 4.5 ± 0.4 a | 5.1 ± 0.7 b | 4.3 ± 0.5 a | 5.1 ± 0.7 b | <0.001 | 0.619 | 0.654 |
Liver | 7.6 ± 1.0 a | 7.1 ± 1.0 b | 7.2 ± 0.6 ab | 7.0 ± 0.8 b | 0.039 | 0.147 | 0.351 |
Heart | 0.47 ± 0.06 a | 0.51 ± 0.05 b | 0.47 ± 0.05 a | 0.51 ± 0.07 b | 0.003 | 0.904 | 0.745 |
Brain to liver ratio | 0.59 ± 0.10 a | 0.74 ± 0.16 b | 0.60 ± 0.09 a | 0.75 ± 0.16 b | <0.001 | 0.905 | 0.937 |
Values are means ± SD. Means that do not share a common superscript letter differ at p < 0.05. Significant p-values are bolded. ALC, alcohol exposed; CON, control.