. 2022 Apr 14;23(8):4352. doi: 10.3390/ijms23084352

Table 1.

Classification of CD11c⁺MHCII⁺ dendritic cells.

Type	Anatomical Sites	Surface Markers				Main Functions
Type	Anatomical Sites	CD4	CD8α	CD205	CD11b	Main Functions
Lymphoid	Thymus, spleen, lymph nodes	−	high	+	−	Induction of cross-tolerance, antigen cross preservation for the stimulation of cytotoxic response
		+	−	−	+	Lymphocyte polarization toward T helper
		−	−	−	+	Lymphocyte polarization toward T helper
Myeloid	Spleen, lymph nodes, lymphatic system	−	−	+	+	CD4⁺ T cell activation toward T_H1 generation
Myeloid	Spleen, lymph nodes, lymphatic system	−	low	high	−	CD4⁺ T cell activation toward T_H1 generation