INFOBOX Magnetic resonance imaging (MRI) is a non-invasive and ionizing-radiation-free tool to investigate the GI motor function and assess the properties of luminal contents. In this field, MRI is applied for the simultaneous acquisition of parameters such as motility, transit, flow, and fluid distribution, which have a profound impact on drug dissolution and absorption. This investigation can also help in increasing the in vivo relevance of in vitro models. Therefore, MRI is an emerging tool for pharmaceutical sciences.