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. 2022 Apr 6;7(15):13343–13353. doi: 10.1021/acsomega.2c01075

Figure 4.

Figure 4

(A) In vitro release behavior of miconazole nitrate loaded formulations (MCNE11, MNE11, DS) through the dialysis membrane (n = 3). (B) Permeation study across rat skin placed for various formulations (MCNE11, MNE11, MKT, and DS) using Franz diffusion cell (% cumulative permeation). (C) Ex vivo drug retention behavior across the rat skin. (D) Various mechanisms via drug passes from organized skin layers to the deeper layers. MKT stands for the marketed product (conventional cream) miconazole.