Table 1.
Demographic and epidemiological characteristics, according to the occurrence of general toxicity, of patients with ALL of the Amazon Region.
| Variables | General Toxicity | p Value | |
|---|---|---|---|
| Yes (n. 27) | No (n. 24) | ||
| Gender | |||
| Female | 9 (33.3%) | 13 (54.2%) | 0.134 a |
| Male | 18 (66.7%) | 11 (45.8%) | |
| Age (years) | |||
| Average (±SD) | 7.19 (±4.34) | 6.96 (±4.43) | 0.776 b |
| ALL Sub-type | |||
| ALL B | 23 (37.0%) | 19 (16.7%) | 0.804 a |
| ALL T | 4 (14.8%) | 5 (20.8%) | |
| Ancestry | |||
| European | 0.494 (±0.520) | 0.496 (±0.120) | 0.439 b |
| Amerindian | 0.342 (±0.149) | 0.324 (±0.123) | 0.970 b |
| African | 0.143 (±0.060) | 0.179 (±0.057) | 0.029 b,* |
| Toxicity type | |||
| Gastrointestinal | |||
| Low | 9 (33.3%) | NA | NA |
| Moderate | 8 (29.6%) | NA | |
| High | 0 (0.0%) | NA | |
| Hepatic | |||
| Low | 2 (7.4%) | NA | NA |
| Moderate | 21 (77.7%) | NA | |
| High | 3 (11.1%) | NA | |
| Infectious | |||
| Low | 0 (0.0%) | NA | NA |
| Moderate | 11 (40.7%) | NA | |
| High | 14 (51.8%) | NA | |
| Mortality | |||
| Yes | 6 (22.2%) | 9 (37.5%) | 0.375 a |
| No | 21 (77.8%) | 15 (62.5%) | |
ALL, acute lymphoid leukemia. SD, standard deviation. a Chi-square test. b Mann–Whitney test. * p value ≤ 0.05. NA, not applicable.