TABLE 3.
Distribution of MICs (μg/ml) of 11 antimicrobial agents by geographic area
| Antimicrobial | India (n = 168)
|
Jamaica (n = 41)
|
Mexico (n = 38)
|
Kenya (n = 37)
|
||||
|---|---|---|---|---|---|---|---|---|
| MIC50a | MIC90b | MIC50 | MIC90 | MIC50 | MIC90 | MIC50 | MIC90 | |
| AMP | 8 | >1,024 | 4 | 1,024 | 4 | >1,024 | 4 | 32 |
| DOX | 16 | 64 | 4 | 16 | 32 | 64 | 32 | 128 |
| NAL | 4 | 256 | 4 | 8 | 4 | 4 | 8 | 16 |
| TMP | 256 | 1,024 | 16 | 1,024 | 256 | 512 | 128 | 1,024 |
| SXT | 512 | >1,024 | 8 | 32 | 8 | >1,024 | 64 | 256 |
| CROc | ≤0.0156 | 0.0625 | ≤0.0156 | 0.0625 | ≤0.0156 | 0.0625 | ≤0.0156 | 4 |
| MEC | 0.5 | 16 | 0.125 | 8 | 0.125 | 8 | 0.5 | 4 |
| CIP | ≤0.0156 | 0.25 | ≤0.0156 | 0.0312 | ≤0.0156 | ≤0.0156 | ≤0.0156 | 0.0312 |
| LVX | 0.0625 | 1 | 0.0625 | 0.25 | 0.0625 | 0.0625 | ≤0.0156 | 0.25 |
| AZMc | ≤0.0156 | ≤0.0156 | ≤0.0156 | ≤0.0156 | ≤0.0156 | ≤0.0156 | 0.5 | 2 |
| RFX | 16 | 32 | 16 | 32 | 16 | 32 | 16 | 256 |
a
MIC50, MIC required to inhibit the growth of 50% of the strains tested.
b
MIC90, MIC required to inhibit the growth of 90% of the strains tested.
c
Data for CRO and AZM are based on 268 pathogens. Sixteen isolates (non-cholera causing vibrios, P. shigelloides, and Aeromonas spp.) from India were not included in this part of the study.