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. 2022 Apr 2;14(4):778. doi: 10.3390/pharmaceutics14040778

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Schematic of liposomes coated with polymers. (a) Schematic of the configuration of low-molecular-weight HA/liposome complex. Reprinted with permission from Ref. [113]. Copyright © 2015, American Chemical Society. (b) Liposomes modified with hyaluronic acid–ceramide (HA–CE), whereas multiple hydrophobic anchors were introduced to HA. Reprinted with permission from Ref. [114]. Copyright © 2013 Elsevier B.V. All rights reserved. (c) Layer-by-layer (LbL) deposition of appositively charged polyelectrolytes. Enhanced therapeutic efficacy was obtained under optimized LbL deposition conditions. Reprinted with permission from Ref. [115]. Copyright © 2019, American Chemical Society. (d) Polymer-caged liposomes. Liposomes were modified with poly(acrylic acid)-cholesterol, followed by cross-linking with diamine. Reprinted with permission from Ref. [116]. Copyright © 2007, American Chemical Society.