Table 2.
Comparisons of the SARS-CoV-2 S1-specific antibody levels in plasma between symptomatic paediatric and adult patients with mild disease.
| Plasma | ||||||||
|---|---|---|---|---|---|---|---|---|
| Days Post Diagnosis | IgA | 0–4 | 5–9 | 12–16 | 19–23 | 26–30 | 83–99 | 169–197 |
| Symptomatic paediatric patients | n | 6 | 4 | 9 | 12 | 11 | 10 | 10 |
| Median ± IQR | 1.1 ± 1.4 | 2.9 ± 3.6 | 5.2 ± 5.3 | 10.9 ± 11.2 | 11.0 ± 11.5 | 2.5 ± 3.7 | 1.9 ± 2.8 | |
| % | 50 | 100 | 100 | 92 | 91 | 80 | 90 | |
| Adult patients with mild disease | n | 7 | 8 | 4 | 1 | 0 | 1 | 0 |
| Median ± IQR | 0.2 ± 0.3 | 2.2 ± 4.9 | 2.9 ± 7.3 | 8.2 | 2.4 | - | ||
| % | 14 | 63 | 75 | 100 | - | 100 | - | |
| Mann-Whitney test between groups | p value | 0.0082 | 0.8081 | 0.5035 | - | - | - | - |
| Fisher’s Exact test between groups | p value | 0.2657 | 0.4909 | 0.3077 | - | - | - | - |
| IgG | ||||||||
| Symptomatic paediatric patients | n | 6 | 4 | 9 | 12 | 11 | 10 | 10 |
| Median ± IQR | 0.1 ± 0.1 | 1.0 ± 1.1 | 1.3 ± 3.0 | 5.2 ± 4.7 | 7.0 ± 4.8 | 4.8 ± 6.6 | 2.3 ± 3.2 | |
| % | 0 | 50 | 67 | 83 | 100 | 80 | 90 | |
| Adult with mild disease | n | 7 | 8 | 4 | 1 | 0 | 1 | 0 |
| Median ± IQR | 0.1 ± 0.0 | 0.3 ± 0.7 | 1.5 ± 1.8 | 10.8 | - | 1.1 | - | |
| % | 0 | 13 | 75 | 100 | - | 0 | - | |
| Mann-Whitney test between groups | p value | 0.0734 | 0.2828 | 0.8252 | - | - | - | - |
| Fisher’s Exact test between groups | p value | ns | 0.2364 | ns | - | - | - | - |