Skip to main content
. 2022 Apr 8;11(4):499. doi: 10.3390/antibiotics11040499

Figure 2.

Figure 2

Ciprofloxacin resistance evolution of three N. gonorrhoeae clones of WHO-F (A,C,E) and three clones of WHO-P (B,D,F) over time. The MIC’s of ciprofloxacin were tested using E-test (bioMerieux, Marcy-l’Étoile, France) once there was visible growth. Once there was visible growth, the ciprofloxacin MIC’s were tested using E-Test (bioMerieux, Marcy-l’Étoile, France) and the next plate was inoculated. The initial MIC of all clones was 0.004 mg/L. The red cross indicates the sampling time that was subjected to WGS. The black squares represent the duration of the mutation noted next to them for as long as the days displayed in the axis below them.