Figure 3.

Vascular endothelial function and plasma biomarkers of nitric oxide homeostasis in MetS persons who followed a DGA-based diet containing potatoes (DGA + POTATO) or bagels (DGA + BAGEL) for 2 w prior to completing an oral glucose tolerance test. (A) Brachial artery FMD, and plasma (B) NOx, (C) ARG, (D) ADMA/ARG, (E) SDMA/ARG, and (F) homoARG/ARG during a 2-h postprandial period following the ingestion of 75 g of glucose. Data (means ± SE, n = 27) are expressed as changes from baseline (0 min) and were analyzed by 2-way RM ANOVA with Bonferroni’s post-test to assess effects due to time, treatment, and their interaction. p < 0.05 was considered statistically significant, and data are annotated (a > b > c) to visualize post-hoc effects due to time or time × treatment as appropriate. Abbreviations: ADMA, asymmetric dimethylarginine; ARG, arginine; DGA, Dietary Guidelines for Americans; FMD, flow-mediated dilation; homoARG, homoarginine; MetS, metabolic syndrome; NOx, nitric oxide metabolites (sum of nitrate and nitrite); and SDMA, symmetric dimethylarginine.