Figure 5.

Mitochondria from L1/201 mice showed normal mobility and enhanced velocity but moved more retrogradely than mitochondria from wild-type neurons. Mitochondrial velocity (A), mobility (B) and transport direction (C) were analyzed in cultured cerebellar neurons from 7-day-old male L1-201 mice and wild-type littermates. Mean values ± SD are shown; n = 3. * p < 0.05, *** p < 0.005 (velocity: Mann–Whitney test; mobility: two-way ANOVA with Tukey´s post-hoc test; direction: Kruskal–Wallis test with Dunn’s multiple comparison test).