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. 2022 Apr 8;13:860268. doi: 10.3389/fgene.2022.860268

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Copyright © 2022 Hou, Xu, Liu, Yang, Li, Zhao and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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mRNAsi differences in different clinicopathological features. (A) Differences in the mRNAsi between normal and LUAD tissues. (B) Differences in the mRNAsi between different lymph node metastasis. (C) Differences in the mRNAsi among different T stages. (D) Comparison of the mRNAsi among four AJCC stages. (E) Protein–protein interactions between 22 hub genes in turquoise module. The thickness of the solid line represents the strength of the relationship. (F) Differential expression of 22 hub genes between normal and tumor cases in the LUAD dataset of TCGA shown by box-plots.