Table 2.
Comparisons of age, MR-derived perfusion parameters, and tumor size data between patients with lymphoma and TET and between thymoma and thymic carcinoma.
| Variable | Lymphoma (n = 17) |
TET (n = 45) | p Value | Thymoma (n = 31) | Thymic Carcinoma (n = 14) |
p Value |
|---|---|---|---|---|---|---|
| Age (yr) | 30 (26, 48) | 59 (52, 65) | <0.001 *† | 56 (49, 65) | 62 (55, 69) | 0.169 |
| Ktrans (10−3 min−1) | 0.34 (0.11, 1.13) | 0.46 (0.22, 0.62) | 0.664 | 0.36 (0.17, 0.58) | 0.51 (0.45, 1.50) | 0.042 * |
| Kep (10−3 min−1) | 0.86 (0.67, 1.73) | 1.70 (0.90, 2.96) | 0.073 | 2.72 (1.14, 4.71) | 0.93 (0.72, 1.38) | 0.005 *† |
| Vp (10−3) | 0.01 (0.01, 0.03) | 0.02 (0.01, 0.05) | 0.444 | 0.02 (0.01, 0.05) | 0.03 (0.02, 0.07) | 0.086 |
| Ve (10−3) | 0.39 (0.13, 1.01) | 0.20 (0.08, 0.54) | 0.253 | 0.13 (0.06, 0.31) | 0.52 (0.20, 2.36) | 0.001 *† |
| TTP (× 102 s) | 1.29 (1.05, 1.96) | 1.09 (0.76, 1.75) | 0.087 | 0.89 (0.66, 1.29) | 1.72 (1.01, 1.96) | 0.003 *† |
| Max. conc. (10−3 mM) | 32 (18, 47) | 21 (11, 38) | 0.246 | 17 (9, 33) | 31 (16, 70) | 0.062 |
| Tumor volume (× 104 mm3) | 4.50 (2.06, 6.37) | 1.21 (0.57, 4.52) | 0.028 * | 1.10 (0.49, 4.40) | 1.60 (0.67, 5.06) | 0.624 |
| Surface area (× 104 mm2) | 2.49 (1.55, 3.84) | 0.80 (0.44, 2.78) | 0.027 * | 0.72 (0.42, 2.86) | 1.14 (0.55, 2.80) | 0.573 |
| Max. diameter (× 102 mm) | 0.76 (0.65, 1.02) | 0.45 (0.35, 0.71) | 0.001 *† | 0.43 (0.35, 0.72) | 0.51 (0.41, 0.72) | 0.315 |
Data are presented as median (inter-quartiles) and compared between two groups using the Mann–Whitney U test. Key: Kep = efflux rate constant from tissue EES into the blood plasma; Ktrans = efflux rate constant from blood plasma into the tissue EES; Vp = blood plasma volume per unit volume of tissue; Ve = EEs volume per unit volume of tissue; TTP = time to the peak of the concentration curve; TET = thymic epithelial tumor. * p < 0.05. † indicated significant difference after controlling the false discovery rate.