Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The independent variables and levels employed as low (0), medium (−1), and high (+1) in statistical optimization of β-SIT-Alg/Ch-NPs-FA.
| Independent Variables | Level Employed | ||
|---|---|---|---|
| Low (−1) | Medium (0) | High (+1) | |
| X1: Chitosan (% w/v) | 0.1 | 0.2 | 0.3 |
| X2: Sodium alginate (% w/v) | 0.2 | 0.4 | 0.6 |
| X3: Calcium chloride (mM) | 16 | 24 | 32 |
| Dependent Variables | |||
| Y1: Particle size (nm) | Minimize | ||
| Y2: Drug encapsulation (%) | Maximize | ||
| Y3: Drug release (%) | Maximize | ||
