Table 1.
Experimental (Log-P) | Average ± SD |
---|---|
At 35 °C, pH = 6.5 | 1.65 ± 0.029 |
At Room temperature/ambient temperature, pH = 6.5 | 1.58 ± 0.019 |
Experimental (Log-P) | Avg. Log-P ± SD |
At 35 °C, pH = 7.1 | 1.68 ± 0.013 |
At Room temperature/ambient temperature, pH = 7.1 | 1.54 ± 0.149 |
Experimental (Log-P) | Avg. Log-P ± SD |
At 35 °C, pH = 8.8 | 0.94 ± 0.023 |
At Room temperature/ambient temperature, pH = 8.8 | 0.88 ± 0.060 |
Predicted (cLogP) | Predicted value |
ChemDraw Version 16.0 | 2.53 |
Swiss ADME | 3.04 |